3rcw

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(New page: '''Unreleased structure''' The entry 3rcw is ON HOLD Authors: Filippakopoulos, P., Keates, T., Picaud, S., Felletar, I., Pike, A.C.W., Krojer, T., von Delf, F., Arrowsmith, C.H., Edward...)
Current revision (12:18, 14 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 3rcw is ON HOLD
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==Crystal Structure of the bromodomain of human BRD1==
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<StructureSection load='3rcw' size='340' side='right'caption='[[3rcw]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3rcw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RCW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MB3:1-METHYLPYRROLIDIN-2-ONE'>MB3</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rcw OCA], [https://pdbe.org/3rcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rcw RCSB], [https://www.ebi.ac.uk/pdbsum/3rcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rcw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BRD1_HUMAN BRD1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.<ref>PMID:16387653</ref> <ref>PMID:21880731</ref>
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Authors: Filippakopoulos, P., Keates, T., Picaud, S., Felletar, I., Pike, A.C.W., Krojer, T., von Delf, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Knapp, S., Structural Genomics Consortium (SGC)
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==See Also==
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*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
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Description: Crystal Structure of the bromodomain of human BRD1
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra C]]
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[[Category: Edwards AM]]
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[[Category: Felletar I]]
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[[Category: Filippakopoulos P]]
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[[Category: Keates T]]
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[[Category: Knapp S]]
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[[Category: Krojer T]]
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[[Category: Picaud S]]
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[[Category: Pike ACW]]
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[[Category: Weigelt J]]
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[[Category: Von Delft F]]

Current revision

Crystal Structure of the bromodomain of human BRD1

PDB ID 3rcw

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