3mw7

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:02, 6 September 2023) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3mw7.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-UMP(produced from 5-fluoro-6-amino-UMP)==
-
The line below this paragraph, containing "STRUCTURE_3mw7", creates the "Structure Box" on the page.
+
<StructureSection load='3mw7' size='340' side='right'caption='[[3mw7]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3mw7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MW7 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.32&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5FU:5-FLUORO-URIDINE-5-MONOPHOSPHATE'>5FU</scene></td></tr>
-
{{STRUCTURE_3mw7| PDB=3mw7 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mw7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw7 OCA], [https://pdbe.org/3mw7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mw7 RCSB], [https://www.ebi.ac.uk/pdbsum/3mw7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mw7 ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/UMPS_HUMAN UMPS_HUMAN] Defects in UMPS are the cause of orotic aciduria type 1 (ORAC1) [MIM:[https://omim.org/entry/258900 258900]. A disorder of pyrimidine metabolism resulting in megaloblastic anemia and orotic acid crystalluria that is frequently associated with some degree of physical and mental retardation. A minority of cases have additional features, particularly congenital malformations and immune deficiencies.<ref>PMID:9042911</ref>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/UMPS_HUMAN UMPS_HUMAN]
-
===Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-UMP, produced from 5-fluoro-6-amino-UMP===
+
==See Also==
-
 
+
*[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]]
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
[[3mw7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW7 OCA].
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Orotidine-5'-phosphate decarboxylase]]
+
[[Category: Large Structures]]
-
[[Category: Kotra, L P.]]
+
[[Category: Kotra LP]]
-
[[Category: Liu, Y.]]
+
[[Category: Liu Y]]
-
[[Category: Pai, E F.]]
+
[[Category: Pai EF]]

Current revision

Crystal structure of human orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-UMP(produced from 5-fluoro-6-amino-UMP)

PDB ID 3mw7

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3mw7"
Personal tools