We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.
Dynactin
From Proteopedia
(Difference between revisions)
(New page: Crystal Structure of Dynactin, 2hkq {{STRUCTURE_2hkq| PDB=2hkq | SIZE=300| |right|CAPTION=Dynactin subunit 1 CAP-Gly domain complex with protein...) |
|||
| (35 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | <StructureSection load='2hl5' size='350' side='right' scene='44/444636/Cv/1' caption='Dynactin subunit 1 CAP-Gly domain (magenta and yellow) complex with the C-terminal domain of human EB1 (cyan and green) and chloride ion [[2hl5]]'> | ||
| - | + | __TOC__ | |
| - | + | ||
| - | + | == Function == | |
| - | + | '''Dynactin''' (DCTN) is a multi-subunit protein which modulates the binding of dynein to cell organelles which are to be transported along microtubules.<ref>PMID:1836789</ref> See also [[CAP-Gly domain]]. | |
| + | |||
| + | == Disease == | ||
| + | |||
| + | Mutant dynactin was found in motor neuron disease.<ref>PMID:12627231</ref> | ||
| + | |||
| + | |||
| + | == Structural highlights == | ||
| + | <scene name='44/444636/Cv/3'>Dynactin subunit 1 CAP-Gly domain with the C-terminal domain of human EB1</scene> ([[2hl5]]).<ref>PMID:16949363</ref> | ||
== 3D Structures of Dynactin == | == 3D Structures of Dynactin == | ||
| + | [[Dynactin 3D structures]] | ||
| + | |||
| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| + | |||
| + | == References == | ||
| + | <references/> | ||
| + | </StructureSection> | ||
| + | [[Category:Topic Page]] | ||
Current revision
| |||||||||||
