2rqk

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2rqk" [edit=sysop:move=sysop])
Current revision (07:05, 1 May 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2rqk.png|left|200px]]
 
-
<!--
+
==NMR Solution Structure of Mesoderm Development (MESD) - closed conformation==
-
The line below this paragraph, containing "STRUCTURE_2rqk", creates the "Structure Box" on the page.
+
<StructureSection load='2rqk' size='340' side='right'caption='[[2rqk]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2rqk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RQK FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rqk OCA], [https://pdbe.org/2rqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rqk RCSB], [https://www.ebi.ac.uk/pdbsum/2rqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rqk ProSAT]</span></td></tr>
-
{{STRUCTURE_2rqk| PDB=2rqk | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===NMR Solution Structure of Mesoderm Development (MESD) - closed conformation===
+
[https://www.uniprot.org/uniprot/MESD_MOUSE MESD_MOUSE] Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.<ref>PMID:12581525</ref> <ref>PMID:21397183</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21397185}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 21397185 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rq/2rqk_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_21397185}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rqk ConSurf].
-
[[2rqk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RQK OCA].
+
<div style="clear:both"></div>
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:21397185</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Andersen, O M.]]
+
[[Category: Andersen OM]]
-
[[Category: Diehl, A.]]
+
[[Category: Diehl A]]
-
[[Category: Holdener, B C.]]
+
[[Category: Holdener BC]]
-
[[Category: Koehler, C.]]
+
[[Category: Koehler C]]
-
[[Category: Lighthouse, J K.]]
+
[[Category: Lighthouse JK]]
-
[[Category: Oschkinat, H.]]
+
[[Category: Oschkinat H]]
-
[[Category: Schmieder, P.]]
+
[[Category: Schmieder P]]
-
[[Category: Werther, T.]]
+
[[Category: Werther T]]

Current revision

NMR Solution Structure of Mesoderm Development (MESD) - closed conformation

PDB ID 2rqk

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2rqk"
Personal tools