2lbs

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'''Unreleased structure'''
 
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The entry 2lbs is ON HOLD
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==Solution structure of double-stranded RNA binding domain of S. cerevisiae RNase III (Rnt1p) in complex with AAGU tetraloop hairpin==
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<StructureSection load='2lbs' size='340' side='right'caption='[[2lbs]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2lbs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LBS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LBS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lbs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lbs OCA], [https://pdbe.org/2lbs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lbs RCSB], [https://www.ebi.ac.uk/pdbsum/2lbs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lbs ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNT1_YEAST RNT1_YEAST] DsRNA-specific nuclease that cleaves eukaryotic pre-ribosomal RNA at the U3 snoRNP-dependent A0 site in the 5'-external transcribed spacer (ETS) and in the 3'-ETS. In vitro, cleaves synthetic 5'-ETS RNA A0 site in the absence of snoRNA or other factors. Has an essential growth function in addition to pre-rRNA processing.
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Authors: Wang, Z., Hartman, E., Roy, K., Chanfreau, G., Feigon, J.
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==See Also==
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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Description: Structure of a yeast RNase III dsRBD complex with a non-canonical RNA substrate provides new insights into substrate recognition
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Chanfreau G]]
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[[Category: Feigon J]]
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[[Category: Hartman E]]
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[[Category: Roy K]]
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[[Category: Wang Z]]

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Solution structure of double-stranded RNA binding domain of S. cerevisiae RNase III (Rnt1p) in complex with AAGU tetraloop hairpin

PDB ID 2lbs

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