Ribozyme
From Proteopedia
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| - | + | <StructureSection load='' size='350' scene='Ribozyme/Cv/3' side='right' caption='Hammerhead ribozyme, (PDB-ID [[379d]])'> | |
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| - | Ribozyme (RZ) is an RNA molecule which catalyzes a chemical reaction. | + | [[Ribozyme]] (RZ) is an RNA molecule which catalyzes a chemical reaction<ref>PMID:9224568</ref>.<br /> |
| + | *'''Glucosamine-6-phosphate activated RZ''' (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites.<br /> | ||
| + | *'''Leadzyme''' is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see [[Student Projects for UMass Chemistry 423 Spring 2012-10]].<br /> | ||
| + | *'''Hairpin RZ''' and '''hammerhead RZ''' are named based on their shape<ref>PMID:9849614</ref>.<br /> | ||
| + | *'''Group I intron''' catalyzes its own selfish splicing<ref>PMID:2197983</ref>. | ||
| + | * Comparative genomic analysis revealed '''Twister''', '''Twister sister''', '''Hatchet''', and '''Pistol''' <ref>PMID:24240507</ref><ref>PMID:26167874 </ref>. | ||
| - | {{TOC limit|limit=2}} | ||
| - | == 3D Structures of Ribozyme == | + | |
| + | Articles in Proteopedia concerning ribozymes include: | ||
| + | *[[Azoarcus group I intron]] | ||
| + | *[[Kink-turn motif]] | ||
| + | *[[Ribosome]] | ||
| + | *[[Large Ribosomal Subunit of Haloarcula|The Large Ribosomal Subunit]] | ||
| + | *[[Hairpin Ribozyme]] | ||
| + | *[[Journal:JBIC:24|Human CPEB3 ribozyme's P4 domain]] | ||
| + | <br> | ||
| + | |||
| + | To view automatically PDB-IDs concerning ribozymes, see: | ||
| + | *[[:Category:Ribozyme|Ribozyme]] | ||
| + | *[[:Category:Catalytic rna|Catalytic RNA]] | ||
| + | *[[:Category:GlmS|GlmS]] | ||
| + | *[[:Category:Hammerhead|Hammerhead]] | ||
| + | *[[:Category:Hairpin|Hairpin]] | ||
| + | *[[:Category:Hepatitis delta|Hepatitis delta virus]] | ||
| + | *[[:Category:Twister|Twister]] | ||
| + | *[[:Category:Twister sister|Twister sister]] | ||
| + | *[[:Category:Hatchet|Hatchet]] | ||
| + | *[[:Category:Pistol|Pistol]] | ||
| + | *[[:Category:Group i intron|Group I intron]] | ||
| + | *[[:Category:Varkud satellite|Varkud satellite]] | ||
| + | |||
| + | </StructureSection> | ||
| + | == 3D Structures of Ribozymes == | ||
| + | [[Ribozyme 3D structures]] | ||
| + | |||
| + | == References == | ||
| + | <references/> | ||
| + | [[Category: Topic Page]] | ||
Current revision
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3D Structures of Ribozymes
References
- ↑ Tang J, Breaker RR. Rational design of allosteric ribozymes. Chem Biol. 1997 Jun;4(6):453-9. PMID:9224568
- ↑ Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci. 1998 Nov;54(11):1175-202. PMID:9849614 doi:http://dx.doi.org/10.1007/s000180050247
- ↑ Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990;59:543-68. PMID:2197983 doi:http://dx.doi.org/10.1146/annurev.bi.59.070190.002551
- ↑ Roth A, Weinberg Z, Chen AG, Kim PB, Ames TD, Breaker RR. A widespread self-cleaving ribozyme class is revealed by bioinformatics. Nat Chem Biol. 2014 Jan;10(1):56-60. doi: 10.1038/nchembio.1386. Epub 2013 Nov, 17. PMID:24240507 doi:http://dx.doi.org/10.1038/nchembio.1386
- ↑ Weinberg Z, Kim PB, Chen TH, Li S, Harris KA, Lunse CE, Breaker RR. New classes of self-cleaving ribozymes revealed by comparative genomics analysis. Nat Chem Biol. 2015 Aug;11(8):606-10. doi: 10.1038/nchembio.1846. Epub 2015 Jul, 13. PMID:26167874 doi:http://dx.doi.org/10.1038/nchembio.1846
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