2dej
From Proteopedia
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- | [[Image:2dej.jpg|left|200px]]<br /><applet load="2dej" size="350" color="white" frame="true" align="right" spinBox="true" | ||
- | caption="2dej, resolution 1.50Å" /> | ||
- | '''Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose'''<br /> | ||
- | == | + | ==Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose== |
- | + | <StructureSection load='2dej' size='340' side='right'caption='[[2dej]], [[Resolution|resolution]] 1.50Å' scene=''> | |
- | [ | + | == Structural highlights == |
- | + | <table><tr><td colspan='2'>[[2dej]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DEJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DEJ FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APW:{5-O-[(R)-{[(S)-AMINO(HYDROXY-KAPPAO)PHOSPHORYL]OXY}(HYDROXY-KAPPAO)PHOSPHORYL]ADENOSINATO(2-)}MAGNESIUM'>APW</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dej OCA], [https://pdbe.org/2dej PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dej RCSB], [https://www.ebi.ac.uk/pdbsum/2dej PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dej ProSAT], [https://www.topsan.org/Proteins/RSGI/2dej TOPSAN]</span></td></tr> | |
- | + | </table> | |
- | [ | + | == Function == |
- | [ | + | [https://www.uniprot.org/uniprot/GAL1_PYRHO GAL1_PYRHO] Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).<ref>PMID:16511293</ref> |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | [ | + | Check<jmol> |
- | + | <jmolCheckbox> | |
- | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/de/2dej_consurf.spt"</scriptWhenChecked> |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | [ | + | </jmolCheckbox> |
- | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dej ConSurf]. |
- | [ | + | <div style="clear:both"></div> |
- | + | ==See Also== | |
+ | *[[Galactokinase|Galactokinase]] | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Pyrococcus horikoshii]] | ||
+ | [[Category: Inagaki E]] | ||
+ | [[Category: Sakamoto K]] | ||
+ | [[Category: Shinkai A]] | ||
+ | [[Category: Yokoyama S]] |
Current revision
Crystal Structure of galaktokinase from Pyrococcus horikoshii with AMP-PN and galactose
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