3rgt
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3rgt is ON HOLD Authors: Fedorov, A.A., Fedorov, E.V., Wichelecki, D., Gerlt, J.A., Almo, S.C. Description: Crystal structure of d-mannonate dehydr...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of d-mannonate dehydratase from Chromohalobacter salexigens complexed with D-Arabinohydroxamate== | |
| - | + | <StructureSection load='3rgt' size='340' side='right'caption='[[3rgt]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3rgt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromohalobacter_salexigens Chromohalobacter salexigens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RGT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EZ4:(2S,3R,4R)-2,3,4,5-TETRAHYDROXY-N-OXO-PENTANAMIDE'>EZ4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rgt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rgt OCA], [https://pdbe.org/3rgt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rgt RCSB], [https://www.ebi.ac.uk/pdbsum/3rgt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rgt ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DMGD_CHRSD DMGD_CHRSD] Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chromohalobacter salexigens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Almo SC]] | ||
| + | [[Category: Fedorov AA]] | ||
| + | [[Category: Fedorov EV]] | ||
| + | [[Category: Gerlt JA]] | ||
| + | [[Category: Wichelecki D]] | ||
Current revision
Crystal structure of d-mannonate dehydratase from Chromohalobacter salexigens complexed with D-Arabinohydroxamate
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