3qf7

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[[Image:3qf7.jpg|left|200px]]
 
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==The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair==
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The line below this paragraph, containing "STRUCTURE_3qf7", creates the "Structure Box" on the page.
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<StructureSection load='3qf7' size='340' side='right'caption='[[3qf7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3qf7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QF7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QF7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3qf7| PDB=3qf7 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qf7 OCA], [https://pdbe.org/3qf7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qf7 RCSB], [https://www.ebi.ac.uk/pdbsum/3qf7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qf7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RAD50_THEMA RAD50_THEMA] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site (By similarity).
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===The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair===
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==See Also==
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*[[ATPase 3D structures|ATPase 3D structures]]
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__TOC__
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21458667 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21458667}}
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==About this Structure==
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[[3qf7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QF7 OCA].
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==Reference==
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<ref group="xtra">PMID:21458667</ref><references group="xtra"/>
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Lammens, K.]]
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[[Category: Lammens K]]
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[[Category: Moeckel, C.]]
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[[Category: Moeckel C]]

Current revision

The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair

PDB ID 3qf7

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