2lc3

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'''Unreleased structure'''
 
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The entry 2lc3 is ON HOLD
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==Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A==
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<StructureSection load='2lc3' size='340' side='right'caption='[[2lc3]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2lc3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LC3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LC3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lc3 OCA], [https://pdbe.org/2lc3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lc3 RCSB], [https://www.ebi.ac.uk/pdbsum/2lc3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lc3 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HECD1_HUMAN HECD1_HUMAN] Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity).
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Authors: Lemak, A., Yee, A., Houliston, S., Garcia, M., Arrowsmith, C., Dhe-Paganon, S., Northeast Structural Genomics Consortium (NESG)
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==See Also==
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*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
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Description: Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A (CASP Target)
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith C]]
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[[Category: Dhe-Paganon S]]
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[[Category: Garcia M]]
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[[Category: Houliston S]]
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[[Category: Lemak A]]
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[[Category: Montelione GT]]
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[[Category: Yee A]]

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Solution NMR structure of a helical bundle domain from human E3 ligase HECTD1. Northeast structural genomics consortium (NESG) target HT6305A

PDB ID 2lc3

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