This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3rj8
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3rj8 is ON HOLD Authors: Duskova, J., Skalova, T., Stepankova, A., Koval, T., Hasek, J., Ostergaard, L.H., Fuglsang, C.C., Kolenko, P., Dohnalek, J....) |
|||
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of carbohydrate oxidase from Microdochium nivale== | |
| - | + | <StructureSection load='3rj8' size='340' side='right'caption='[[3rj8]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3rj8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Microdochium_nivale Microdochium nivale]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RJ8 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rj8 OCA], [https://pdbe.org/3rj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rj8 RCSB], [https://www.ebi.ac.uk/pdbsum/3rj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rj8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MNCO_MICNN MNCO_MICNN] Catalyzes the selective oxidation of C1 hydroxyl moieties on mono-, oligo- and polysaccharides with concomitant reduction of molecular oxygen to hydrogen peroxide. This results in the formation of the corresponding lactones, which typically undergo spontaneous hydrolysis. Carbohydrate oxidase is able to oxidize a variety of substrates including D-glucose, D-galactose, D-xylose, D-maltose, D-cellobiose, and lactose. In addition, among various oligosaccharides, the enzyme preferred tetrameric dextrins, indicating a favorable interaction of four linked glucose units with the substrate binding pocket.<ref>PMID:11179980</ref> [PROSITE-ProRule:PRU00718]<ref>PMID:11179980</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Microdochium nivale]] | ||
| + | [[Category: Dohnalek J]] | ||
| + | [[Category: Duskova J]] | ||
| + | [[Category: Fuglsang CC]] | ||
| + | [[Category: Hasek J]] | ||
| + | [[Category: Kolenko P]] | ||
| + | [[Category: Koval T]] | ||
| + | [[Category: Ostergaard LH]] | ||
| + | [[Category: Skalova T]] | ||
| + | [[Category: Stepankova A]] | ||
Current revision
Crystal structure of carbohydrate oxidase from Microdochium nivale
| |||||||||||
