3q7k

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (17:11, 1 November 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3q7k.jpg|left|200px]]
 
-
<!--
+
==Formate Channel FocA from Salmonella typhimurium==
-
The line below this paragraph, containing "STRUCTURE_3q7k", creates the "Structure Box" on the page.
+
<StructureSection load='3q7k' size='340' side='right'caption='[[3q7k]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3q7k]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi_str._CT18 Salmonella enterica subsp. enterica serovar Typhi str. CT18]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7K FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
-
{{STRUCTURE_3q7k| PDB=3q7k | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7k OCA], [https://pdbe.org/3q7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7k RCSB], [https://www.ebi.ac.uk/pdbsum/3q7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7k ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q7CQU0_SALTY Q7CQU0_SALTY]
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The formate transporter FocA was described to switch its mode of operation from a passive export channel at high external pH to a secondary active formate/H(+) importer at low pH. The crystal structure of Salmonella typhimurium FocA at pH 4.0 shows that this switch involves a major rearrangement of the amino termini of individual protomers in the pentameric channel. The amino-terminal helices open or block transport in a concerted, cooperative action that indicates how FocA is gated in a pH-dependent way. Electrophysiological studies show that the protein acts as a specific formate channel at pH 7.0 and that it closes upon a shift of pH to 5.1.
-
===Formate Channel FocA from Salmonella typhimurium===
+
pH-dependent gating in a FocA formate channel.,Lu W, Du J, Wacker T, Gerbig-Smentek E, Andrade SL, Einsle O Science. 2011 Apr 15;332(6027):352-4. PMID:21493860<ref>PMID:21493860</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21493860}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 3q7k" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 21493860 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_21493860}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
[[3q7k]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7K OCA].
+
[[Category: Salmonella enterica subsp. enterica serovar Typhi str. CT18]]
-
 
+
[[Category: Andrade SLA]]
-
==Reference==
+
[[Category: Du J]]
-
<ref group="xtra">PMID:21493860</ref><references group="xtra"/>
+
[[Category: Einsle O]]
-
[[Category: Salmonella enterica subsp. enterica serovar typhi]]
+
[[Category: Gerbig-Smentek E]]
-
[[Category: Andrade, S L.A.]]
+
[[Category: Lue W]]
-
[[Category: Du, J.]]
+
[[Category: Wacker T]]
-
[[Category: Einsle, O.]]
+
-
[[Category: Gerbig-Smentek, E.]]
+
-
[[Category: Lue, W.]]
+
-
[[Category: Wacker, T.]]
+

Current revision

Formate Channel FocA from Salmonella typhimurium

PDB ID 3q7k

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3q7k"
Personal tools