1aqr

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[[Image:1aqr.png|left|200px]]
 
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==CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE==
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The line below this paragraph, containing "STRUCTURE_1aqr", creates the "Structure Box" on the page.
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<StructureSection load='1aqr' size='340' side='right'caption='[[1aqr]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1aqr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AQR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene></td></tr>
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{{STRUCTURE_1aqr| PDB=1aqr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aqr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aqr OCA], [https://pdbe.org/1aqr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aqr RCSB], [https://www.ebi.ac.uk/pdbsum/1aqr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aqr ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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3D solution structural calculations for yeast silver(I)-substituted metallothionein (MT) and native copper(I) MT were completed using experimentally determined NOE and dihedral angle constraints, in conjunction with experimentally derived metal-to-Cys connectivities for AgMT which were assumed identical for CuMT. For the first 40 residues in both structures, the polypeptide backbone wraps around the metal cluster in two large parallel loops separated by a deep cleft containing the metal cluster. Minor differences between the two structures include differences in hydrogen bonds and the orientation of the N-terminus with the overall protein volume conserved to within 6.5%.
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===CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE===
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3D solution structure of copper and silver-substituted yeast metallothioneins.,Peterson CW, Narula SS, Armitage IM FEBS Lett. 1996 Jan 22;379(1):85-93. PMID:8566237<ref>PMID:8566237</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_8566237}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1aqr" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 8566237 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_8566237}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[1aqr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AQR OCA].
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==Reference==
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<ref group="xtra">PMID:008566237</ref><ref group="xtra">PMID:010672009</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Armitage, I M.]]
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[[Category: Armitage IM]]
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[[Category: Narula, S S.]]
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[[Category: Narula SS]]
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[[Category: Peterson, C W.]]
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[[Category: Peterson CW]]
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[[Category: Copper detoxification]]
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[[Category: Metal-thiolate cluster]]
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[[Category: Metallothionein]]
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Current revision

CU-METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE

PDB ID 1aqr

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