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205d

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(New page: 200px<br /><applet load="205d" size="350" color="white" frame="true" align="right" spinBox="true" caption="205d, resolution 2.640&Aring;" /> '''STRUCTURE OF AN RNA...)
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[[Image:205d.jpg|left|200px]]<br /><applet load="205d" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="205d, resolution 2.640&Aring;" />
 
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'''STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP'''<br />
 
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==Overview==
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==STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP==
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The crystal structure of the RNA dodecamer 5'-GGACUUUGGUCC-3' has been, determined from X-ray diffraction data to 2.6 A resolution. This oligomer, forms an asymmetric double helix in the crystal. Four consecutive, non-Watson-Crick base-pairs are formed in the middle of the duplex, including the first intrahelical U-U (or T-T) pairs observed in an, oligonucleotide crystal structure. Two different conformations of U-U, pairs are observed in the context of the surrounding sequence. One of, these pairs is highly twisted, allowing a bound water to bridge across, strands in the major groove. The crystal packing illustrates a new form of, RNA helix-helix interaction.
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<StructureSection load='205d' size='340' side='right'caption='[[205d]], [[Resolution|resolution]] 2.64&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[205d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=205D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=205D FirstGlance]. <br>
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205D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=205D OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=205d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=205d OCA], [https://pdbe.org/205d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=205d RCSB], [https://www.ebi.ac.uk/pdbsum/205d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=205d ProSAT]</span></td></tr>
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==Reference==
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</table>
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Structure of an RNA double helix including uracil-uracil base pairs in an internal loop., Baeyens KJ, De Bondt HL, Holbrook SR, Nat Struct Biol. 1995 Jan;2(1):56-62. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7719854 7719854]
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__TOC__
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[[Category: Protein complex]]
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</StructureSection>
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[[Category: Baeyens, K.J.]]
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[[Category: Large Structures]]
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[[Category: Bondt, H.L.De.]]
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[[Category: Baeyens KJ]]
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[[Category: Holbrook, S.R.]]
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[[Category: De Bondt HL]]
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[[Category: a-rna]]
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[[Category: Holbrook SR]]
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[[Category: double helix]]
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[[Category: internal loop]]
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[[Category: mismatched]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 17:46:57 2008''
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Current revision

STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE PAIRS IN AN INTERNAL LOOP

PDB ID 205d

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