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2fl8

From Proteopedia

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[[Image:2fl8.png|left|200px]]
 
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==Fitting of the gp10 trimer structure into the cryoEM map of the bacteriophage T4 baseplate in the hexagonal conformation.==
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The line below this paragraph, containing "STRUCTURE_2fl8", creates the "Structure Box" on the page.
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<SX load='2fl8' size='340' side='right' viewer='molstar' caption='[[2fl8]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2fl8]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FL8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fl8 OCA], [https://pdbe.org/2fl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fl8 RCSB], [https://www.ebi.ac.uk/pdbsum/2fl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fl8 ProSAT]</span></td></tr>
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{{STRUCTURE_2fl8| PDB=2fl8 | SCENE= }}
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</table>
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== Function ==
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===Fitting of the gp10 trimer structure into the cryoEM map of the bacteriophage T4 baseplate in the hexagonal conformation.===
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[https://www.uniprot.org/uniprot/BP10_BPT4 BP10_BPT4] Baseplate protein that is part of the baseplate wedge and that connects the short tail fibers to the baseplate (PubMed:16554069). During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors. Involved in the tail assembly.<ref>PMID:16554069</ref> <ref>PMID:21129200</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_16554069}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16554069 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/2fl8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16554069}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fl8 ConSurf].
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[[2fl8]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FL8 OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:016554069</ref><references group="xtra"/>
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__TOC__
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[[Category: Enterobacteria phage t4]]
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</SX>
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[[Category: Leiman, P G.]]
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[[Category: Escherichia virus T4]]
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[[Category: Mesyanzhinov, V V.]]
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[[Category: Large Structures]]
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[[Category: Rossmann, M G.]]
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[[Category: Leiman PG]]
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[[Category: Shneider, M M.]]
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[[Category: Mesyanzhinov VV]]
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[[Category: Rossmann MG]]
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[[Category: Shneider MM]]

Current revision

Fitting of the gp10 trimer structure into the cryoEM map of the bacteriophage T4 baseplate in the hexagonal conformation.

2fl8, resolution 12.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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