292d

[[Image:292d.gif|left|200px]]<br /><applet load="292d" size="350" color="white" frame="true" align="right" spinBox="true"

caption="292d, resolution 1.000&Aring;" />

'''INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX'''<br />

==Overview==

The DNA fragment d(CG)3 was co-crystallized with, N-(2-aminoethyl)-1,4-diaminobutane (PA(24], a chemically synthesized, polyamine. The complex crystal contained one polyamine, 3 magnesium, cations and one sodium cation per duplex of d(CG)3, and well diffracted, the X-ray intensities up to 1.0 A resolution. The d(CG)3 took a, left-handed Z-DNA conformation, and the PA(24) molecule electrostatically, interacted with the phosphate groups of the d(CG)3 duplex.

 

==About this Structure==

292D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=P24:'>P24</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=NA:'>NA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=292D OCA].

 

Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex., Ohishi H, Kunisawa S, van der Marel G, van Boom JH, Rich A, Wang AH, Tomita K, Hakoshima T, FEBS Lett. 1991 Jun 24;284(2):238-44. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2060642 2060642]

[[Category: Boom, J.H.Van.]]

[[Category: Hakoshima, T.]]

[[Category: Kunisawa, S.]]

[[Category: Marel, G.Van.Der.]]

[[Category: Ohishi, H.]]

[[Category: Rich, A.]]

[[Category: Tomita, K.]]

[[Category: Wang, A.H.J.]]

[[Category: MG]]

[[Category: P24]]

[[Category: 4-diaminobutane]]