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2a64

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(New page: 200px<br /><applet load="2a64" size="350" color="white" frame="true" align="right" spinBox="true" caption="2a64, resolution 3.300&Aring;" /> '''Crystal Structure o...)
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[[Image:2a64.gif|left|200px]]<br /><applet load="2a64" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2a64, resolution 3.300&Aring;" />
 
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'''Crystal Structure of Bacterial Ribonuclease P RNA'''<br />
 
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==Overview==
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==Crystal Structure of Bacterial Ribonuclease P RNA==
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The x-ray crystal structure of a 417-nt ribonuclease P RNA from Bacillus, stearothermophilus was solved to 3.3-A resolution. This RNA enzyme is, constructed from a number of coaxially stacked helical domains joined, together by local and long-range interactions. These helical domains are, arranged to form a remarkably flat surface, which is implicated by a, wealth of biochemical data in the binding and cleavage of the precursors, of transfer RNA substrate. Previous photoaffinity crosslinking data are, used to position the substrate on the crystal structure and to identify, the chemically active site of the ribozyme. This site is located in a, highly conserved core structure formed by intricately interlaced, long-range interactions between interhelical sequences.
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<StructureSection load='2a64' size='340' side='right'caption='[[2a64]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2a64]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A64 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A64 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a64 OCA], [https://pdbe.org/2a64 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a64 RCSB], [https://www.ebi.ac.uk/pdbsum/2a64 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a64 ProSAT]</span></td></tr>
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</table>
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==About this Structure==
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==See Also==
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2A64 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A64 OCA].
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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Crystal structure of a bacterial ribonuclease P RNA., Kazantsev AV, Krivenko AA, Harrington DJ, Holbrook SR, Adams PD, Pace NR, Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13392-7. Epub 2005 Sep 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16157868 16157868]
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[[Category: Geobacillus stearothermophilus]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Adams, P.D.]]
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[[Category: Adams PD]]
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[[Category: Harrington, D.J.]]
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[[Category: Harrington DJ]]
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[[Category: Holbrook, S.R.]]
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[[Category: Holbrook SR]]
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[[Category: Kazantsev, A.V.]]
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[[Category: Kazantsev AV]]
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[[Category: Krivenko, A.A.]]
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[[Category: Krivenko AA]]
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[[Category: Pace, N.R.]]
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[[Category: Pace NR]]
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[[Category: hydrolase]]
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[[Category: ribonuclease]]
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[[Category: ribozyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jan 29 17:55:16 2008''
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Current revision

Crystal Structure of Bacterial Ribonuclease P RNA

PDB ID 2a64

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