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2yba
From Proteopedia
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| - | [[Image:2yba.png|left|200px]] | ||
| - | + | ==Crystal structure of Nurf55 in complex with histone H3== | |
| - | + | <StructureSection load='2yba' size='340' side='right'caption='[[2yba]], [[Resolution|resolution]] 2.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2yba]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YBA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YBA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yba FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yba OCA], [https://pdbe.org/2yba PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yba RCSB], [https://www.ebi.ac.uk/pdbsum/2yba PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yba ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | === | + | [https://www.uniprot.org/uniprot/CAF1_DROME CAF1_DROME] Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the nucleosome remodeling and deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the nucleosome remodeling factor (NURF) complex, which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin; and the polycomb group (PcG) repressor complex ESC-E(Z), which promotes repression of homeotic genes during development. Also required for transcriptional repression of E2F target genes by E2f2 and Rbf or Rbf2.<ref>PMID:8887645</ref> <ref>PMID:9419341</ref> <ref>PMID:9784495</ref> <ref>PMID:12490953</ref> <ref>PMID:15456884</ref> |
| - | + | == References == | |
| - | + | <references/> | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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| - | == | + | |
| - | [[2yba]] is a 4 chain structure with sequence from [ | + | |
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[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: Aiwazian | + | [[Category: Large Structures]] |
| - | [[Category: Bauer | + | [[Category: Aiwazian J]] |
| - | [[Category: Bouwmeester | + | [[Category: Bauer A]] |
| - | [[Category: Bunker | + | [[Category: Bouwmeester T]] |
| - | [[Category: Chan | + | [[Category: Bunker RD]] |
| - | [[Category: Faty | + | [[Category: Chan H]] |
| - | [[Category: Fischle | + | [[Category: Faty M]] |
| - | [[Category: Gu | + | [[Category: Fischle W]] |
| - | [[Category: Gut | + | [[Category: Gu J]] |
| - | [[Category: Hess | + | [[Category: Gut H]] |
| - | [[Category: Li | + | [[Category: Hess D]] |
| - | [[Category: Lingaraju | + | [[Category: Li L]] |
| - | [[Category: Ly-Hartig | + | [[Category: Lingaraju GM]] |
| - | [[Category: Muller | + | [[Category: Ly-Hartig N]] |
| - | [[Category: Prusty | + | [[Category: Muller J]] |
| - | [[Category: Sack | + | [[Category: Prusty AB]] |
| - | [[Category: Schmitges | + | [[Category: Sack R]] |
| - | [[Category: Stutzer | + | [[Category: Schmitges FW]] |
| - | [[Category: Thoma | + | [[Category: Stutzer A]] |
| - | [[Category: Wirth | + | [[Category: Thoma NH]] |
| - | [[Category: Zhao | + | [[Category: Wirth U]] |
| - | [[Category: Zhou | + | [[Category: Zhao K]] |
| + | [[Category: Zhou S]] | ||
Current revision
Crystal structure of Nurf55 in complex with histone H3
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Categories: Drosophila melanogaster | Large Structures | Aiwazian J | Bauer A | Bouwmeester T | Bunker RD | Chan H | Faty M | Fischle W | Gu J | Gut H | Hess D | Li L | Lingaraju GM | Ly-Hartig N | Muller J | Prusty AB | Sack R | Schmitges FW | Stutzer A | Thoma NH | Wirth U | Zhao K | Zhou S
