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3q2j

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[[Image:3q2j.jpg|left|200px]]
 
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==Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex==
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The line below this paragraph, containing "STRUCTURE_3q2j", creates the "Structure Box" on the page.
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<StructureSection load='3q2j' size='340' side='right'caption='[[3q2j]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3q2j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2J FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1501&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CKI:N-(2-AMINOETHYL)-5-CHLOROISOQUINOLINE-8-SULFONAMIDE'>CKI</scene></td></tr>
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{{STRUCTURE_3q2j| PDB=3q2j | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2j OCA], [https://pdbe.org/3q2j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2j RCSB], [https://www.ebi.ac.uk/pdbsum/3q2j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KKA3_ENTFL KKA3_ENTFL] Resistance to kanamycin and structurally-related aminoglycosides, including amikacin.
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===Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex===
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==See Also==
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*[[Phosphotransferase 3D structures|Phosphotransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3q2j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2J OCA].
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[[Category: Enterococcus faecalis]]
[[Category: Enterococcus faecalis]]
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[[Category: Kanamycin kinase]]
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[[Category: Large Structures]]
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[[Category: Berghuis, A M.]]
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[[Category: Berghuis AM]]
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[[Category: Fong, D H.]]
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[[Category: Fong DH]]
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[[Category: Hwang, J.]]
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[[Category: Hwang J]]
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[[Category: Xiong, B.]]
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[[Category: Xiong B]]

Current revision

Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa Protein Kinase Inhibitor CKI-7 Complex

PDB ID 3q2j

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