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3rtl

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[[Image:3rtl.jpg|left|200px]]
 
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==Staphylococcus aureus heme-bound IsdB-N2==
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The line below this paragraph, containing "STRUCTURE_3rtl", creates the "Structure Box" on the page.
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<StructureSection load='3rtl' size='340' side='right'caption='[[3rtl]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3rtl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RTL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.453&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3rtl| PDB=3rtl | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rtl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rtl OCA], [https://pdbe.org/3rtl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rtl RCSB], [https://www.ebi.ac.uk/pdbsum/3rtl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rtl ProSAT]</span></td></tr>
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</table>
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===Staphylococcus aureus heme-bound IsdB-N2===
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== Function ==
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[https://www.uniprot.org/uniprot/ISDB_STAAN ISDB_STAAN] Seems to function as the primary receptor for hemoglobin since its inactivation inhibits the ability of S.aureus to bind hemoglobin. Binds hemoglobin in a dose-dependent way. Required for S.aureus growth using hemoglobin as the sole iron source. Also required for virulence. IsdA and/or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity).
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3rtl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus Staphylococcus aureus subsp. aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RTL OCA].
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus]]
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[[Category: Staphylococcus aureus subsp. aureus N315]]
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[[Category: Arrieta, A L.]]
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[[Category: Arrieta AL]]
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[[Category: Gaudin, C F.M.]]
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[[Category: Gaudin CFM]]
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[[Category: Grigg, J C.]]
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[[Category: Grigg JC]]
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[[Category: Murphy, M E.P.]]
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[[Category: Murphy MEP]]

Current revision

Staphylococcus aureus heme-bound IsdB-N2

PDB ID 3rtl

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