2ld5
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2ld5 is ON HOLD Authors: Zhang, Y. Description: Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA== | |
| + | <StructureSection load='2ld5' size='340' side='right'caption='[[2ld5]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2ld5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LD5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ld5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ld5 OCA], [https://pdbe.org/2ld5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ld5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ld5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ld5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/HXA13_MOUSE HXA13_MOUSE] Defects in Hoxa13 are the cause of hypodactyly (Hd), a condition characterized by profound deficiency of digital arch structures. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HXA13_MOUSE HXA13_MOUSE] Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Hox protein|Hox protein]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA
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