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3rbf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form== | |
| + | <StructureSection load='3rbf' size='340' side='right'caption='[[3rbf]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3rbf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RBF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rbf OCA], [https://pdbe.org/3rbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rbf RCSB], [https://www.ebi.ac.uk/pdbsum/3rbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rbf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/DDC_HUMAN DDC_HUMAN] Aromatic L-amino acid decarboxylase deficiency. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DDC_HUMAN DDC_HUMAN] Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. | ||
| - | + | ==See Also== | |
| - | + | *[[DOPA decarboxylase|DOPA decarboxylase]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Borri Voltattorni C]] | ||
| + | [[Category: Cellini B]] | ||
| + | [[Category: Cutruzzola F]] | ||
| + | [[Category: Gianni S]] | ||
| + | [[Category: Giardina G]] | ||
| + | [[Category: Montioli R]] | ||
| + | [[Category: Paiardini A]] | ||
Current revision
Crystal structure of Human aromatic L-amino acid decarboxylase (AADC) in the apo form
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