3pja

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[[Image:3pja.png|left|200px]]
 
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==Crystal structure of human C3PO complex==
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The line below this paragraph, containing "STRUCTURE_3pja", creates the "Structure Box" on the page.
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<StructureSection load='3pja' size='340' side='right'caption='[[3pja]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pja]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PJA FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pja OCA], [https://pdbe.org/3pja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pja RCSB], [https://www.ebi.ac.uk/pdbsum/3pja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pja ProSAT]</span></td></tr>
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{{STRUCTURE_3pja| PDB=3pja | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of human C3PO complex===
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[https://www.uniprot.org/uniprot/TSN_HUMAN TSN_HUMAN] DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref> Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.<ref>PMID:9111049</ref> <ref>PMID:21552258</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21552258 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21552258}}
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==About this Structure==
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[[3pja]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJA OCA].
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==Reference==
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<ref group="xtra">PMID:021552258</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Huang, N.]]
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[[Category: Large Structures]]
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[[Category: Zhang, H.]]
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[[Category: Huang N]]
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[[Category: Zhang H]]

Current revision

Crystal structure of human C3PO complex

PDB ID 3pja

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OCA

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