3qxy
From Proteopedia
(Difference between revisions)
												
			
			| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3qxy.jpg|left|200px]]  | ||
| - | <  | + | ==Human SETD6 in complex with RelA Lys310==  | 
| - | + | <StructureSection load='3qxy' size='340' side='right'caption='[[3qxy]], [[Resolution|resolution]] 2.09Å' scene=''>  | |
| - | + | == Structural highlights ==  | |
| - | + | <table><tr><td colspan='2'>[[3qxy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QXY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QXY FirstGlance]. <br>  | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr>  | |
| - | -->  | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>  | 
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qxy OCA], [https://pdbe.org/3qxy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qxy RCSB], [https://www.ebi.ac.uk/pdbsum/3qxy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qxy ProSAT]</span></td></tr>  | |
| + | </table>  | ||
| + | == Function ==  | ||
| + | [https://www.uniprot.org/uniprot/SETD6_HUMAN SETD6_HUMAN] Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.<ref>PMID:21131967</ref>   | ||
| - | ==  | + | ==See Also==  | 
| - | + | *[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]]  | |
| - | + | == References ==  | |
| - | + | <references/>  | |
| - | + | __TOC__  | |
| - | + | </StructureSection>  | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | [[  | + | |
| - | + | ||
| - | ==  | + | |
| - | <  | + | |
[[Category: Homo sapiens]]  | [[Category: Homo sapiens]]  | ||
| - | [[Category: Chang  | + | [[Category: Large Structures]]  | 
| - | [[Category: Cheng  | + | [[Category: Chang Y]]  | 
| - | [[Category: Gozani  | + | [[Category: Cheng X]]  | 
| - | [[Category: Horton  | + | [[Category: Gozani O]]  | 
| - | [[Category: Levy  | + | [[Category: Horton JR]]  | 
| - | [[Category: Peng  | + | [[Category: Levy D]]  | 
| - | [[Category: Zhang  | + | [[Category: Peng J]]  | 
| + | [[Category: Zhang X]]  | ||
Current revision
Human SETD6 in complex with RelA Lys310
  | |||||||||||
Categories: Homo sapiens | Large Structures | Chang Y | Cheng X | Gozani O | Horton JR | Levy D | Peng J | Zhang X
