3p13

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[[Image:3p13.jpg|left|200px]]
 
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==Complex Structure of D-ribose Pyranase Sa240 with D-ribose==
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The line below this paragraph, containing "STRUCTURE_3p13", creates the "Structure Box" on the page.
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<StructureSection load='3p13' size='340' side='right'caption='[[3p13]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3p13]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P13 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RIP:RIBOSE(PYRANOSE+FORM)'>RIP</scene></td></tr>
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{{STRUCTURE_3p13| PDB=3p13 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p13 OCA], [https://pdbe.org/3p13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p13 RCSB], [https://www.ebi.ac.uk/pdbsum/3p13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p13 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RBSD_STAA8 RBSD_STAA8] Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.[HAMAP-Rule:MF_01661]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Ribose is transported into cells in its pyranose form and must be rearranged to its furanose form for further utilization. Ribose pyranase RbsD catalyzes the conversion of ribose from the pyranose to furanose form. This is the key step for substrate supply to ribokinase RbsK, which converts ribose to ribose-5-phosphate for further metabolism. Sequence analysis indicated Sa240 from Staphylococcus aureus was a ribose pyranase homolog. Here we showed that Sa240 formed dimeric structure both in solution and in crystal. S240-ribose complex structure showed a ribose binding site formed by an incomplete active site compared with RbsD. Because the catalytic activity of ribose pyranase depends on its oligomeric state, we propose Sa240 is catalytically inactive in its dimeric structure.
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===Complex Structure of D-ribose Pyranase Sa240 with D-ribose===
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Crystal structure of Sa240: A ribose pyranase homolog with partial active site from Staphylococcus aureus.,Wang L, Wu M, Zang J J Struct Biol. 2011 May;174(2):413-9. Epub 2011 Jan 27. PMID:21276853<ref>PMID:21276853</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_21276853}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3p13" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 21276853 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21276853}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3p13]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P13 OCA].
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[[Category: Staphylococcus aureus subsp. aureus NCTC 8325]]
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[[Category: Wang L]]
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==Reference==
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[[Category: Wu M]]
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<ref group="xtra">PMID:021276853</ref><references group="xtra"/>
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[[Category: Zang J]]
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[[Category: Staphylococcus aureus]]
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[[Category: Wang, L.]]
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[[Category: Wu, M.]]
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[[Category: Zang, J.]]
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Current revision

Complex Structure of D-ribose Pyranase Sa240 with D-ribose

PDB ID 3p13

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