3qox

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[[Image:3qox.jpg|left|200px]]
 
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==DOT1L structure in complex with SAH==
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The line below this paragraph, containing "STRUCTURE_3qox", creates the "Structure Box" on the page.
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<StructureSection load='3qox' size='340' side='right'caption='[[3qox]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qox]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QOX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QOX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_3qox| PDB=3qox | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qox FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qox OCA], [https://pdbe.org/3qox PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qox RCSB], [https://www.ebi.ac.uk/pdbsum/3qox PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qox ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
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===DOT1L structure in complex with SAH===
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==See Also==
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*[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_21564555}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 21564555 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21564555}}
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==About this Structure==
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[[3qox]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QOX OCA].
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==Reference==
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<ref group="xtra">PMID:021564555</ref><references group="xtra"/>
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[[Category: Histone-lysine N-methyltransferase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Jin, L.]]
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[[Category: Large Structures]]
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[[Category: Jin L]]

Current revision

DOT1L structure in complex with SAH

PDB ID 3qox

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OCA

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