This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2zqa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2zqa" [edit=sysop:move=sysop])
Current revision (13:48, 1 November 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2zqa.png|left|200px]]
 
-
<!--
+
==Cefotaxime acyl-intermediate structure of class a beta-lacta Toho-1 E166A/R274N/R276N triple mutant==
-
The line below this paragraph, containing "STRUCTURE_2zqa", creates the "Structure Box" on the page.
+
<StructureSection load='2zqa' size='340' side='right'caption='[[2zqa]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2zqa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZQA FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.95&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CEF:CEFOTAXIME,+C3+CLEAVED,+OPEN,+BOUND+FORM'>CEF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
{{STRUCTURE_2zqa| PDB=2zqa | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zqa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zqa OCA], [https://pdbe.org/2zqa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zqa RCSB], [https://www.ebi.ac.uk/pdbsum/2zqa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zqa ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX] Has strong cefotaxime-hydrolyzing activity.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zq/2zqa_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zqa ConSurf].
 +
<div style="clear:both"></div>
-
===Cefotaxime acyl-intermediate structure of class a beta-lacta Toho-1 E166A/R274N/R276N triple mutant===
+
==See Also==
-
 
+
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[2zqa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZQA OCA].
+
-
[[Category: Beta-lactamase]]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Ishii, Y.]]
+
[[Category: Large Structures]]
-
[[Category: Matsuzawa, H.]]
+
[[Category: Ishii Y]]
-
[[Category: Miyano, M.]]
+
[[Category: Matsuzawa H]]
-
[[Category: Nitanai, Y.]]
+
[[Category: Miyano M]]
-
[[Category: Shimamura, T.]]
+
[[Category: Nitanai Y]]
-
[[Category: Takehira, M.]]
+
[[Category: Shimamura T]]
-
[[Category: Uchiyama, T.]]
+
[[Category: Takehira M]]
-
[[Category: Yutani, K.]]
+
[[Category: Uchiyama T]]
-
[[Category: Acyl-enzyme]]
+
[[Category: Yutani K]]
-
[[Category: Antibiotic resistance]]
+
-
[[Category: Beta-lactamase]]
+
-
[[Category: Cefotaxime]]
+
-
[[Category: Complex]]
+
-
[[Category: Esbl]]
+
-
[[Category: Extended-spectrum]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Plasmid]]
+
-
[[Category: Toho-1]]
+

Current revision

Cefotaxime acyl-intermediate structure of class a beta-lacta Toho-1 E166A/R274N/R276N triple mutant

PDB ID 2zqa

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2zqa"
Personal tools