2wm8

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[[Image:2wm8.png|left|200px]]
 
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==Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987)==
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The line below this paragraph, containing "STRUCTURE_2wm8", creates the "Structure Box" on the page.
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<StructureSection load='2wm8' size='340' side='right'caption='[[2wm8]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2wm8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WM8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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{{STRUCTURE_2wm8| PDB=2wm8 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wm8 OCA], [https://pdbe.org/2wm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wm8 RCSB], [https://www.ebi.ac.uk/pdbsum/2wm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wm8 ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF HUMAN MAGNESIUM-DEPENDENT PHOSPHATASE 1 OF THE HALOACID DEHALOGENASE SUPERFAMILY (MGC5987)===
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== Function ==
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[https://www.uniprot.org/uniprot/MGDP1_HUMAN MGDP1_HUMAN] Magnesium-dependent phosphatase which may act as a tyrosine phosphatase.
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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[[2wm8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WM8 OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wm/2wm8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wm8 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Arrowsmith C]]
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[[Category: Bray, J E.]]
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[[Category: Bountra C]]
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[[Category: Burgess-Brown, N.]]
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[[Category: Bray JE]]
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[[Category: Chaikuad, A.]]
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[[Category: Burgess-Brown N]]
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[[Category: Delft, F Von.]]
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[[Category: Chaikuad A]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Filippakopoulos, P.]]
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[[Category: Filippakopoulos P]]
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[[Category: Hapka, E.]]
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[[Category: Hapka E]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann U]]
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[[Category: Pike, A C.W.]]
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[[Category: Pike ACW]]
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[[Category: Pilka, E W.]]
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[[Category: Pilka EW]]
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[[Category: Shafqat, N.]]
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[[Category: Shafqat N]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Yue, W W.]]
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[[Category: Yue WW]]
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[[Category: Alternative splicing]]
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[[Category: Von Delft F]]
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[[Category: Haloacid dehalogenase]]
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[[Category: Hydrolase]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Protein phosphatase]]
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Current revision

Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987)

PDB ID 2wm8

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