3pgl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:40, 21 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3pgl.png|left|200px]]
 
-
<!--
+
==Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole==
-
The line below this paragraph, containing "STRUCTURE_3pgl", creates the "Structure Box" on the page.
+
<StructureSection load='3pgl' size='340' side='right'caption='[[3pgl]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3pgl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PGL FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=RZX:2-[(R)-{[4-(3-METHOXYPROPOXY)-3-METHYLPYRIDIN-2-YL]METHYL}SULFINYL]-1H-BENZIMIDAZOLE'>RZX</scene></td></tr>
-
{{STRUCTURE_3pgl| PDB=3pgl | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pgl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pgl OCA], [https://pdbe.org/3pgl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pgl RCSB], [https://www.ebi.ac.uk/pdbsum/3pgl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pgl ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CTDS1_HUMAN CTDS1_HUMAN] Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.<ref>PMID:12721286</ref> <ref>PMID:15681389</ref>
-
===Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole===
+
==See Also==
-
 
+
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
-
 
+
== References ==
-
<!--
+
<references/>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21348431}}, adds the Publication Abstract to the page
+
__TOC__
-
(as it appears on PubMed at http://www.pubmed.gov), where 21348431 is the PubMed ID number.
+
</StructureSection>
-
-->
+
-
{{ABSTRACT_PUBMED_21348431}}
+
-
 
+
-
==About this Structure==
+
-
[[3pgl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PGL OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:021348431</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Phosphoprotein phosphatase]]
+
[[Category: Large Structures]]
-
[[Category: Burstein, G.]]
+
[[Category: Burstein G]]
-
[[Category: Cho, E J.]]
+
[[Category: Cho EJ]]
-
[[Category: Siegel, D.]]
+
[[Category: Siegel D]]
-
[[Category: Zhang, M.]]
+
[[Category: Zhang M]]
-
[[Category: Zhang, Y.]]
+
[[Category: Zhang Y]]

Current revision

Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole

PDB ID 3pgl

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3pgl"
Personal tools