3s54
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3s54 is ON HOLD Authors: Tie, Y.-F., Wang, Y.-F., Weber, I.T. Description: HIV-1 PROTEASE TRIPLE MUTANTS V32I, I47V, V82I WITH ANTIVIRAL DRUG DARUN...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212== | |
| + | <StructureSection load='3s54' size='340' side='right'caption='[[3s54]], [[Resolution|resolution]] 1.42Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3s54]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S54 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=017:(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE'>017</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s54 OCA], [https://pdbe.org/3s54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s54 RCSB], [https://www.ebi.ac.uk/pdbsum/3s54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s54 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q7SSI0_9HIV1 Q7SSI0_9HIV1] | ||
| - | + | ==See Also== | |
| - | + | *[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Human immunodeficiency virus 1]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Tie Y-F]] | ||
| + | [[Category: Wang Y-F]] | ||
| + | [[Category: Weber IT]] | ||
Current revision
HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212
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