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3qh0

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[[Image:3qh0.png|left|200px]]
 
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==X-ray crystal structure of palmitic acid bound to the cyclooxygenase channel of cyclooxygenase-2==
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The line below this paragraph, containing "STRUCTURE_3qh0", creates the "Structure Box" on the page.
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<StructureSection load='3qh0' size='340' side='right'caption='[[3qh0]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qh0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QH0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKR:ACRYLIC+ACID'>AKR</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=COH:PROTOPORPHYRIN+IX+CONTAINING+CO'>COH</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=HSQ:2-(ACETYLAMINO)-2-DEOXY-ALPHA-L-IDOPYRANOSE'>HSQ</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
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{{STRUCTURE_3qh0| PDB=3qh0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qh0 OCA], [https://pdbe.org/3qh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qh0 RCSB], [https://www.ebi.ac.uk/pdbsum/3qh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qh0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PGH2_MOUSE PGH2_MOUSE] Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.<ref>PMID:12925531</ref> <ref>PMID:20463020</ref> <ref>PMID:20810665</ref> <ref>PMID:21489986</ref>
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===X-ray crystal structure of palmitic acid bound to the cyclooxygenase channel of cyclooxygenase-2===
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==See Also==
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*[[Cyclooxygenase 3D structures|Cyclooxygenase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21467029 is the PubMed ID number.
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</StructureSection>
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_21467029}}
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==About this Structure==
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[[3qh0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QH0 OCA].
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==Reference==
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<ref group="xtra">PMID:021467029</ref><references group="xtra"/>
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Prostaglandin-endoperoxide synthase]]
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[[Category: Malkowski MG]]
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[[Category: Malkowski, M G.]]
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[[Category: Vecchio AJ]]
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[[Category: Vecchio, A J.]]
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Current revision

X-ray crystal structure of palmitic acid bound to the cyclooxygenase channel of cyclooxygenase-2

PDB ID 3qh0

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