This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3sal

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3sal" [edit=sysop:move=sysop])
Current revision (17:24, 1 November 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 3sal is ON HOLD
+
==Crystal Structure of Influenza A Virus Neuraminidase N5==
 +
<StructureSection load='3sal' size='340' side='right'caption='[[3sal]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3sal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/duck/Alberta/60/1976(H12N5)) Influenza A virus (A/duck/Alberta/60/1976(H12N5))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SAL FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sal OCA], [https://pdbe.org/3sal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sal RCSB], [https://www.ebi.ac.uk/pdbsum/3sal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sal ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A1ILL9_I76A2 A1ILL9_I76A2]
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
There are 9 serotypes of neuraminidase (NA) from influenza A virus (N1 to N9), which are classified into two groups based on primary sequences (groups 1 and 2). The structural hallmark of the two groups is the presence or absence of an extra 150-cavity (formed by the 150-loop) in the active site. Thus far, structures of NAs from 6 out of the 9 serotypes have been solved. Here, we solved the N5 structure, the last unknown structure group 1 serotype with a unique Asn147 residue in its 150-loop, demonstrating that it has an extended 150-cavity that closes upon inhibitor binding.
-
Authors: Wang, M.Y., Qi, J.X., Liu, Y., Vavricka, C.J., Wu, Y., Li, Q., Gao, G.F.
+
Influenza a virus n5 neuraminidase has an extended 150-cavity.,Wang M, Qi J, Liu Y, Vavricka CJ, Wu Y, Li Q, Gao GF J Virol. 2011 Aug;85(16):8431-5. Epub 2011 Jun 8. PMID:21653672<ref>PMID:21653672</ref>
-
Description: Influenza A virus neuraminidase N5 has an extended 150-cavity
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 3sal" style="background-color:#fffaf0;"></div>
 +
 
 +
==See Also==
 +
*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Gao GF]]
 +
[[Category: Li Q]]
 +
[[Category: Liu Y]]
 +
[[Category: Qi JX]]
 +
[[Category: Vavricka CJ]]
 +
[[Category: Wang MY]]
 +
[[Category: Wu Y]]

Current revision

Crystal Structure of Influenza A Virus Neuraminidase N5

PDB ID 3sal

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3sal"
Personal tools