3rw9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine== | |
| + | <StructureSection load='3rw9' size='340' side='right'caption='[[3rw9]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3rw9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RW9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DSH:5-S-(3-AMINOPROPYL)-5-THIOADENOSINE'>DSH</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rw9 OCA], [https://pdbe.org/3rw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rw9 RCSB], [https://www.ebi.ac.uk/pdbsum/3rw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rw9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPEE_HUMAN SPEE_HUMAN] Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine. | ||
| - | + | ==See Also== | |
| - | + | *[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ealick SE]] | ||
| + | [[Category: McCloskey DE]] | ||
| + | [[Category: Pegg AE]] | ||
| + | [[Category: Seckute J]] | ||
| + | [[Category: Secrist III JA]] | ||
| + | [[Category: Thomas HJ]] | ||
Current revision
Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine
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