3sbg
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3sbg is ON HOLD Authors: Weber, G., Santos, K., Holton, N., Wahl, M.C. Description: Crystal structure of a spliceosomal protein fragment) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of a Prp8 C-terminal fragment== | |
| + | <StructureSection load='3sbg' size='340' side='right'caption='[[3sbg]], [[Resolution|resolution]] 3.28Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3sbg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.28Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbg OCA], [https://pdbe.org/3sbg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbg RCSB], [https://www.ebi.ac.uk/pdbsum/3sbg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbg ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Holton N]] | ||
| + | [[Category: Santos K]] | ||
| + | [[Category: Wahl MC]] | ||
| + | [[Category: Weber G]] | ||
Current revision
Crystal structure of a Prp8 C-terminal fragment
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