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3sc0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3sc0 is ON HOLD Authors: Koutmos, M., Smith, J.L. Description: Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with M...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin== | |
| - | + | <StructureSection load='3sc0' size='340' side='right'caption='[[3sc0]], [[Resolution|resolution]] 1.95Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3sc0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SC0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COB:CO-METHYLCOBALAMIN'>COB</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sc0 OCA], [https://pdbe.org/3sc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3sc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sc0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/MMAC_HUMAN MMAC_HUMAN] Methylmalonic acidemia with homocystinuria, type cblC. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MMAC_HUMAN MMAC_HUMAN] May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Banerjee R]] | ||
| + | [[Category: Gherasim C]] | ||
| + | [[Category: Koutmos M]] | ||
| + | [[Category: Smith JL]] | ||
Current revision
Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin
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