2l3t
From Proteopedia
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| - | [[Image:2l3t.jpg|left|200px]] | ||
| - | < | + | ==Solution structure of tandem SH2 domain from Spt6== |
| - | + | <StructureSection load='2l3t' size='340' side='right'caption='[[2l3t]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2l3t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L3T FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l3t OCA], [https://pdbe.org/2l3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l3t RCSB], [https://www.ebi.ac.uk/pdbsum/2l3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l3t ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPT6_YEAST SPT6_YEAST] Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression. Essential for viability.<ref>PMID:9450930</ref> <ref>PMID:12934008</ref> <ref>PMID:15531585</ref> <ref>PMID:16455495</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Elongation factor 3D structures|Elongation factor 3D structures]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | [[ | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Liu | + | [[Category: Liu J]] |
| - | [[Category: Shi | + | [[Category: Shi Y]] |
| - | [[Category: Wu | + | [[Category: Wu J]] |
| - | [[Category: Zhang | + | [[Category: Zhang J]] |
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Current revision
Solution structure of tandem SH2 domain from Spt6
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