2l9v
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR structure of the FF domain L24A mutant's folding transition state== | |
| - | + | <StructureSection load='2l9v' size='340' side='right'caption='[[2l9v]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2l9v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L9V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L9V FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l9v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l9v OCA], [https://pdbe.org/2l9v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l9v RCSB], [https://www.ebi.ac.uk/pdbsum/2l9v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l9v ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Baker D]] | ||
| + | [[Category: Fersht AR]] | ||
| + | [[Category: Hansen A]] | ||
| + | [[Category: Kay LE]] | ||
| + | [[Category: Korzhnev DM]] | ||
| + | [[Category: Religa TL]] | ||
| + | [[Category: Vernon RM]] | ||
Current revision
NMR structure of the FF domain L24A mutant's folding transition state
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Categories: Homo sapiens | Large Structures | Baker D | Fersht AR | Hansen A | Kay LE | Korzhnev DM | Religa TL | Vernon RM
