3se4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3se4 is ON HOLD Authors: Thomas, C., Garcia, K.C. Description: human IFNw-IFNAR ternary complex) |
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| - | '''Unreleased structure''' | ||
| - | + | ==human IFNw-IFNAR ternary complex== | |
| + | <StructureSection load='3se4' size='340' side='right'caption='[[3se4]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3se4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SE4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5001Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3se4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3se4 OCA], [https://pdbe.org/3se4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3se4 RCSB], [https://www.ebi.ac.uk/pdbsum/3se4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3se4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/INAR1_HUMAN INAR1_HUMAN] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. | ||
| - | + | ==See Also== | |
| - | + | *[[Interferon 3D structures|Interferon 3D structures]] | |
| - | + | *[[Interferon receptor 3D structures|Interferon receptor 3D structures]] | |
| + | *[[Multiple sclerosis|Multiple sclerosis]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Garcia KC]] | ||
| + | [[Category: Thomas C]] | ||
Current revision
human IFNw-IFNAR ternary complex
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