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3sfx
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3sfx is ON HOLD Authors: Hast, M.A., Beese, L.S. Description: FTase complex 7) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib== | |
| + | <StructureSection load='3sfx' size='340' side='right'caption='[[3sfx]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3sfx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptococcus_neoformans_var._grubii_H99 Cryptococcus neoformans var. grubii H99]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SFX FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3FX:(2R)-3-(CYCLOHEXYLAMINO)-2-HYDROXYPROPANE-1-SULFONIC+ACID'>3FX</scene>, <scene name='pdbligand=FII:[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC+ACID'>FII</scene>, <scene name='pdbligand=JAN:6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE'>JAN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sfx OCA], [https://pdbe.org/3sfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sfx RCSB], [https://www.ebi.ac.uk/pdbsum/3sfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sfx ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q55S71_CRYNB Q55S71_CRYNB] | ||
| - | + | ==See Also== | |
| - | + | *[[Farnesyltransferase 3D structures|Farnesyltransferase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Cryptococcus neoformans var. grubii H99]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Beese LS]] | ||
| + | [[Category: Hast MA]] | ||
Current revision
Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib
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