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3sc0

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[[Image:3sc0.jpg|left|200px]]
 
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==Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin==
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The line below this paragraph, containing "STRUCTURE_3sc0", creates the "Structure Box" on the page.
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<StructureSection load='3sc0' size='340' side='right'caption='[[3sc0]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3sc0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SC0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COB:CO-METHYLCOBALAMIN'>COB</scene></td></tr>
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{{STRUCTURE_3sc0| PDB=3sc0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sc0 OCA], [https://pdbe.org/3sc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3sc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sc0 ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin===
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== Disease ==
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[https://www.uniprot.org/uniprot/MMAC_HUMAN MMAC_HUMAN] Methylmalonic acidemia with homocystinuria, type cblC. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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==About this Structure==
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[https://www.uniprot.org/uniprot/MMAC_HUMAN MMAC_HUMAN] May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12).
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[[3sc0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SC0 OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Koutmos, M.]]
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[[Category: Large Structures]]
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[[Category: Smith, J L.]]
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[[Category: Banerjee R]]
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[[Category: Cblc]]
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[[Category: Gherasim C]]
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[[Category: Cobalamin]]
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[[Category: Koutmos M]]
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[[Category: Flavin]]
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[[Category: Smith JL]]
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[[Category: Flavin reductase]]
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[[Category: Glutathione]]
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[[Category: Maturase]]
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[[Category: Mmachc]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin

PDB ID 3sc0

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