2g3w
From Proteopedia
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(New page: 200px<br /><applet load="2g3w" size="350" color="white" frame="true" align="right" spinBox="true" caption="2g3w, resolution 1.90Å" /> '''The Crystal Structur...) |
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| - | [[Image:2g3w.gif|left|200px]]<br /><applet load="2g3w" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2g3w, resolution 1.90Å" /> | ||
| - | '''The Crystal Structure of YaeQ Protein from Xanthomonas axonopodis pv. citri'''<br /> | ||
| - | == | + | ==The Crystal Structure of YaeQ Protein from Xanthomonas axonopodis pv. citri== |
| - | + | <StructureSection load='2g3w' size='340' side='right'caption='[[2g3w]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [ | + | <table><tr><td colspan='2'>[[2g3w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_citri Xanthomonas citri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G3W FirstGlance]. <br> |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g3w OCA], [https://pdbe.org/2g3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g3w RCSB], [https://www.ebi.ac.uk/pdbsum/2g3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g3w ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| - | [[ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g3/2g3w_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2g3w ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The YaeQ family of proteins are found in many Gram-negative and a few Gram-positive bacteria. We have determined the first structure of a member of the YaeQ family by X-ray crystallography. Comparisons with other structures indicate that YaeQ represents a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif found in type II endonucleases and enzymes involved in DNA replication, repair, and recombination. We show that catalytically important residues in the PD-(D/E)XK nuclease superfamily are spatially conserved in YaeQ and other highly conserved YaeQ residues may be poised to interact with nucleic acid structures. | ||
| - | + | Structure of Xanthomonas axonopodis pv. citri YaeQ reveals a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif.,Guzzo CR, Nagem RA, Barbosa JA, Farah CS Proteins. 2007 Nov 15;69(3):644-51. PMID:17623842<ref>PMID:17623842</ref> | |
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 2g3w" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Xanthomonas citri]] | ||
| + | [[Category: Barbosa JARG]] | ||
| + | [[Category: Farah CS]] | ||
| + | [[Category: Guzzo CR]] | ||
| + | [[Category: Nagem RAP]] | ||
Current revision
The Crystal Structure of YaeQ Protein from Xanthomonas axonopodis pv. citri
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