3rfv

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[[Image:3rfv.png|left|200px]]
 
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==Crystal structure of Uronate dehydrogenase from Agrobacterium tumefaciens complexed with NADH and product==
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The line below this paragraph, containing "STRUCTURE_3rfv", creates the "Structure Box" on the page.
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<StructureSection load='3rfv' size='340' side='right'caption='[[3rfv]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3rfv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_fabrum_str._C58 Agrobacterium fabrum str. C58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RFV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15L:GALACTARO-1,5-LACTONE'>15L</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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{{STRUCTURE_3rfv| PDB=3rfv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rfv OCA], [https://pdbe.org/3rfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rfv RCSB], [https://www.ebi.ac.uk/pdbsum/3rfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rfv ProSAT]</span></td></tr>
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</table>
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===Crystal structure of Uronate dehydrogenase from Agrobacterium tumefaciens complexed with NADH and product===
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== Function ==
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[https://www.uniprot.org/uniprot/URODH_AGRFC URODH_AGRFC] Catalyzes the oxidation of D-galacturonate and D-glucuronate to galactarate and D-glucarate, respectively. In fact, in water solution the substrate D-galacturonate is predominantly in pyranosic form whose beta anomer is converted by the enzyme to D-galactaro-1,5-lactone; in solution, this reaction product rearranges to the more stable D-galactaro-1,4-lactone. Makes part of the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. Cannot use NADP(+) instead of NAD(+) as cosubstrate. Is not active on D-galactose, D-glucose, D-galactonate and D-gluconate.<ref>PMID:19060141</ref> <ref>PMID:19921179</ref> <ref>PMID:21676870</ref>
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_21676870}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21676870 is the PubMed ID number.
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</StructureSection>
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[[Category: Agrobacterium fabrum str. C58]]
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{{ABSTRACT_PUBMED_21676870}}
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[[Category: Large Structures]]
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[[Category: Parkkinen T]]
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==About this Structure==
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[[Category: Rouvinen J]]
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[[3rfv]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RFV OCA].
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==Reference==
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<ref group="xtra">PMID:021676870</ref><references group="xtra"/>
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[[Category: Agrobacterium tumefaciens]]
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[[Category: Uronate dehydrogenase]]
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[[Category: Parkkinen, T.]]
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[[Category: Rouvinen, J.]]
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[[Category: Nad binding]]
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[[Category: Oxidoreductase]]
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[[Category: Rossmann fold]]
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[[Category: Ternary complex]]
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Current revision

Crystal structure of Uronate dehydrogenase from Agrobacterium tumefaciens complexed with NADH and product

PDB ID 3rfv

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