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3b0p
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| - | '''Unreleased structure''' | ||
| - | + | ==tRNA-dihydrouridine synthase from Thermus thermophilus== | |
| - | + | <StructureSection load='3b0p' size='340' side='right'caption='[[3b0p]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3b0p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B0P FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b0p OCA], [https://pdbe.org/3b0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b0p RCSB], [https://www.ebi.ac.uk/pdbsum/3b0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b0p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DUSAL_THET8 DUSAL_THET8] Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.[HAMAP-Rule:MF_02041]<ref>PMID:22123979</ref> <ref>PMID:25902496</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermus thermophilus HB8]] | ||
| + | [[Category: Nakamura A]] | ||
| + | [[Category: Tanaka I]] | ||
| + | [[Category: Tanaka Y]] | ||
| + | [[Category: Yamashita K]] | ||
| + | [[Category: Yao M]] | ||
| + | [[Category: Yu F]] | ||
Current revision
tRNA-dihydrouridine synthase from Thermus thermophilus
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