3shw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide== | |
| + | <StructureSection load='3shw' size='340' side='right'caption='[[3shw]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3shw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SHW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SHW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3shw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3shw OCA], [https://pdbe.org/3shw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3shw RCSB], [https://www.ebi.ac.uk/pdbsum/3shw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3shw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ZO1_HUMAN ZO1_HUMAN] The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.<ref>PMID:21240187</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Connexin 3D structure|Connexin 3D structure]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen J]] | ||
| + | [[Category: Pan L]] | ||
| + | [[Category: Yu H]] | ||
| + | [[Category: Yu J]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide
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Categories: Homo sapiens | Large Structures | Chen J | Pan L | Yu H | Yu J | Zhang M
