2l2i

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[[Image:2l2i.jpg|left|200px]]
 
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==NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF==
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The line below this paragraph, containing "STRUCTURE_2l2i", creates the "Structure Box" on the page.
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<StructureSection load='2l2i' size='340' side='right'caption='[[2l2i]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2l2i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L2I FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l2i OCA], [https://pdbe.org/2l2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l2i RCSB], [https://www.ebi.ac.uk/pdbsum/2l2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l2i ProSAT]</span></td></tr>
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{{STRUCTURE_2l2i| PDB=2l2i | SCENE= }}
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</table>
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== Function ==
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===NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF===
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[https://www.uniprot.org/uniprot/TFB1_YEAST TFB1_YEAST] Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.<ref>PMID:7961739</ref> <ref>PMID:8631896</ref>
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[2l2i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2I OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Saccharomyces cerevisiae s288c]]
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[[Category: Large Structures]]
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[[Category: Lafrance-Vanasse, J.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Lello, P Di.]]
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[[Category: Di Lello P]]
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[[Category: Mas, C.]]
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[[Category: Lafrance-Vanasse J]]
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[[Category: Omichinski, J G.]]
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[[Category: Mas C]]
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[[Category: Activator]]
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[[Category: Omichinski JG]]
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[[Category: Erythroid kruppel-like factor eklf]]
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[[Category: Gene expression regulation]]
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[[Category: Mutation]]
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[[Category: Protein structure]]
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[[Category: Transcription]]
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[[Category: Transcription factor tfiih]]
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Current revision

NMR Structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of EKLF

PDB ID 2l2i

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