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3spc
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3spc is ON HOLD Authors: Hansen, S.B., Tao, X., MacKinnon, R. Description: Inward rectifier potassium channel (Kir) 2.2 in complex with dioctanoylg...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Inward rectifier potassium channel Kir2.2 in complex with dioctanoylglycerol pyrophosphate (DGPP)== | |
| + | <StructureSection load='3spc' size='340' side='right'caption='[[3spc]], [[Resolution|resolution]] 2.45Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3spc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.454Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=P8P:(2R)-3-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIOCTANOATE'>P8P</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spc OCA], [https://pdbe.org/3spc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spc RCSB], [https://www.ebi.ac.uk/pdbsum/3spc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KCJ12_CHICK KCJ12_CHICK] Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification is probably due to the blockage of outward current by cytoplasmic polyamines and/or magnesium ions.<ref>PMID:20019282</ref> <ref>PMID:21874019</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Potassium channel 3D structures|Potassium channel 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Gallus gallus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hansen SB]] | ||
| + | [[Category: MacKinnon R]] | ||
| + | [[Category: Tao X]] | ||
Current revision
Inward rectifier potassium channel Kir2.2 in complex with dioctanoylglycerol pyrophosphate (DGPP)
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