1vt9

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[[Image:1vt9.jpg|left|200px]]
 
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==The structure and hydration of the A-DNA fragment D(GGGTACCC) at room temperature and low temperature==
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The line below this paragraph, containing "STRUCTURE_1vt9", creates the "Structure Box" on the page.
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<StructureSection load='1vt9' size='340' side='right'caption='[[1vt9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1vt9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VT9 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vt9 OCA], [https://pdbe.org/1vt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vt9 RCSB], [https://www.ebi.ac.uk/pdbsum/1vt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vt9 ProSAT]</span></td></tr>
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{{STRUCTURE_1vt9| PDB=1vt9 | SCENE= }}
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The DNA fragment d(GGGTACCC) was crystallized as an A-DNA duplex in the hexagonal space group P6(1). The structure was analyzed at room temperature and low temperature (100K) at a resolution of 2.5 A. The helical conformations at the two temperatures are similar but the low-temperature structure is more economically hydrated than the room-temperature one. The structure of d(GGGTACCC) is compared to those of d(GGGTGCCC) and d(GGGCGCCC). This series of molecules, which consists of a mismatched duplex and its two Watson-Crick analogues, exhibits three conformational variants of the A-form of DNA, which are correlated with the specific intermolecular interactions observed in the various crystals. The largest differences in local conformation are displayed by the stacking geometries of the central pyrimidine-purine and the flanking purine-pyrimidine sites in each of the three duplexes. Stacking energy calculations performed on the crystal structures show that the mismatched duplex is destabilized with respect to each of the error-free duplexes, in accordance with helix-coil transition measurements.
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===The structure and hydration of the A-DNA fragment D(GGGTACCC) at room temperature and low temperature===
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The structure and hydration of the A-DNA fragment d(GGGTACCC) at room temperature and low temperature.,Eisenstein M, Frolow F, Shakked Z, Rabinovich D Nucleic Acids Res. 1990 Jun 11;18(11):3185-94. PMID:2356117<ref>PMID:2356117</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1vt9" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 2356117 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_2356117}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[1vt9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VT9 OCA].
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[[Category: Eisenstein M]]
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[[Category: Frolow F]]
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==Reference==
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[[Category: Rabinovich D]]
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<ref group="xtra">PMID:002356117</ref><references group="xtra"/>
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[[Category: Shakked Z]]
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[[Category: Eisenstein, M.]]
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[[Category: Frolow, F.]]
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[[Category: Rabinovich, D.]]
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[[Category: Shakked, Z.]]
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[[Category: A-dna]]
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[[Category: Dna]]
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[[Category: Double helix]]
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Current revision

The structure and hydration of the A-DNA fragment D(GGGTACCC) at room temperature and low temperature

PDB ID 1vt9

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