1vtv

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[[Image:1vtv.jpg|left|200px]]
 
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==Molecular structure of (M5DC-DG)3: The role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA==
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The line below this paragraph, containing "STRUCTURE_1vtv", creates the "Structure Box" on the page.
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<StructureSection load='1vtv' size='340' side='right'caption='[[1vtv]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1vtv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VTV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene></td></tr>
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{{STRUCTURE_1vtv| PDB=1vtv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vtv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vtv OCA], [https://pdbe.org/1vtv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vtv RCSB], [https://www.ebi.ac.uk/pdbsum/1vtv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vtv ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The hexamer (m5 dC-dG)3 has been synthesized and its three-dimensional structure determined by a single crystal X-ray diffraction analysis. The structure has been refined to a final R value of 15.6% at 1.3 A resolution. The molecule forms a left-handed Z-DNA helix which is similar to the unmethylated Z-DNA structure. The presence of the methyl group has resulted in slight changes in the twist angle between successive base pairs and modification of some of the interatomic contacts. Methylation of cytosine in the C5 position is associated with a relative destabilization of the B-DNA structure and a stabilization through hydrophobic bonding of the Z-DNA structure.
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===Molecular structure of (M5DC-DG)3: The role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA===
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Molecular structure of (m5 dC-dG)3: the role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA.,Fujii S, Wang AH, van der Marel G, van Boom JH, Rich A Nucleic Acids Res. 1982 Dec 11;10(23):7879-92. PMID:7155900<ref>PMID:7155900</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_7155900}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1vtv" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 7155900 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_7155900}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[1vtv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTV OCA].
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[[Category: Fujii S]]
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[[Category: Rich A]]
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==Reference==
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[[Category: Van Boom JH]]
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<ref group="xtra">PMID:007155900</ref><references group="xtra"/>
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[[Category: Van Der Marel GA]]
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[[Category: Boom, J H.Van.]]
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[[Category: Wang AH-J]]
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[[Category: Fujii, S.]]
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[[Category: Marel, G A.Van Der.]]
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[[Category: Rich, A.]]
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[[Category: Wang, A H.J.]]
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[[Category: Dna]]
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[[Category: Double helix]]
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[[Category: Modified]]
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[[Category: Z-dna]]
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Current revision

Molecular structure of (M5DC-DG)3: The role of the methyl group on 5-methyl cytosine in stabilizing Z-DNA

PDB ID 1vtv

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