3pzf

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[[Image:3pzf.png|left|200px]]
 
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==1.75A resolution structure of Serpin-2 from Anopheles gambiae==
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The line below this paragraph, containing "STRUCTURE_3pzf", creates the "Structure Box" on the page.
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<StructureSection load='3pzf' size='340' side='right'caption='[[3pzf]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pzf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PZF FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pzf OCA], [https://pdbe.org/3pzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pzf RCSB], [https://www.ebi.ac.uk/pdbsum/3pzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pzf ProSAT]</span></td></tr>
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{{STRUCTURE_3pzf| PDB=3pzf | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SP2_ANOGA SP2_ANOGA] Serine protease inhibitor that functions in the melanization-mediated immune response (PubMed:16113656, PubMed:20953892, PubMed:33520733, PubMed:33045027, PubMed:21465556, PubMed:25525260). By preventing the activation of phenoloxidases through the inhibiting of serine proteases CLIPB9 and CLIPB10, negatively regulates melanization in the hemolymph (PubMed:16113656, PubMed:20953892, PubMed:33520733, PubMed:33045027, PubMed:21465556, PubMed:25525260). By preventing melanization, has a detrimental role during P.berghei parasite mediated-infection and invasion of the mosquito midgut (PubMed:16113656).<ref>PMID:16113656</ref> <ref>PMID:20953892</ref> <ref>PMID:21465556</ref> <ref>PMID:25525260</ref> <ref>PMID:33045027</ref> <ref>PMID:33520733</ref>
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===1.75A resolution structure of Serpin-2 from Anopheles gambiae===
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==See Also==
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*[[Serpin 3D structures|Serpin 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[3pzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anopheles_gambiae Anopheles gambiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PZF OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:021465556</ref><references group="xtra"/>
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[[Category: Anopheles gambiae]]
[[Category: Anopheles gambiae]]
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[[Category: An, C.]]
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[[Category: Large Structures]]
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[[Category: Battaile, K P.]]
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[[Category: An C]]
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[[Category: Lovell, S.]]
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[[Category: Battaile KP]]
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[[Category: Michel, K.]]
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[[Category: Lovell S]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Michel K]]
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[[Category: Melanization]]
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[[Category: Protease inhibitor]]
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[[Category: Serpin]]
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Current revision

1.75A resolution structure of Serpin-2 from Anopheles gambiae

PDB ID 3pzf

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