3pl0

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[[Image:3pl0.png|left|200px]]
 
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==Crystal structure of a bsmA homolog (Mpe_A2762) from Methylobium petroleophilum PM1 at 1.91 A resolution==
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The line below this paragraph, containing "STRUCTURE_3pl0", creates the "Structure Box" on the page.
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<StructureSection load='3pl0' size='340' side='right'caption='[[3pl0]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3pl0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methylibium_petroleiphilum_PM1 Methylibium petroleiphilum PM1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PL0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_3pl0| PDB=3pl0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pl0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pl0 OCA], [https://pdbe.org/3pl0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pl0 RCSB], [https://www.ebi.ac.uk/pdbsum/3pl0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pl0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A2SJH7_METPP A2SJH7_METPP]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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PF10014 is a novel family of 2-oxyglutarate-Fe(2+) -dependent dioxygenases that are involved in biosynthesis of antibiotics and regulation of biofilm formation, likely by catalyzing hydroxylation of free amino acids or other related ligands. The crystal structure of a PF10014 member from Methylibium petroleiphilum at 1.9 A resolution shows strong structural similarity to cupin dioxygenases in overall fold and active site, despite very remote homology. However, one of the beta-strands of the cupin catalytic core is replaced by a loop that displays conformational isomerism that likely regulates the active site.
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===Crystal structure of a bsmA homolog (Mpe_A2762) from Methylobium petroleophilum PM1 at 1.91 A resolution===
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Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site.,Xu Q, Grant J, Chiu HJ, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA Proteins. 2014 Jan;82(1):164-70. doi: 10.1002/prot.24362. Epub 2013 Sep 10. PMID:23852666<ref>PMID:23852666</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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==About this Structure==
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</div>
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[[3pl0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methylibium_petroleiphilum Methylibium petroleiphilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PL0 OCA].
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<div class="pdbe-citations 3pl0" style="background-color:#fffaf0;"></div>
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[[Category: Methylibium petroleiphilum]]
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== References ==
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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<references/>
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[[Category: Biofilm formation]]
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__TOC__
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[[Category: Biosynthetic protein]]
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</StructureSection>
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[[Category: Double-stranded beta-helix fold]]
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[[Category: Large Structures]]
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[[Category: Jcsg]]
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[[Category: Methylibium petroleiphilum PM1]]
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[[Category: Joint center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Quorum sensing]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of a bsmA homolog (Mpe_A2762) from Methylobium petroleophilum PM1 at 1.91 A resolution

PDB ID 3pl0

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